Escape of TLR5 Recognition by Leptospira spp.: A Rationale for Atypical Endoflagella

Holzapfel M, Bonhomme  D, Cagliero  J, Vernel-Pauillac  F, Fanton d’Andon M, Bortolussi S, Fiette  L, Goarant C, Wunder EA Jr, Picardeau M, Ko  AI, Werling D, Matsui M, Boneca IG, Werts C
Front Immunol. 2020 Aug 11;11:2007
doi: 10.3389/fimmu.2020.02007

Use of Golden Syrian Hamster as an Animal Model to Study Leptospirosis-Associated Immune Responses.
Cagliero J, Huet K, Matsui M.
Methods Mol Biol 2020;2134:243-255
doi: 10.1007/978-1-0716-0459-5_22

Health Challenges of the Pacific Region: Insights From History, Geography, Social Determinants, Genetics, and the Microbiome.
Horwood PF, Tarantola A, Goarant  C, Matsui M, Klement E, Umezaki M, Navarro S, Greenhill AG 
Front Immunol. 2019 Sep 13;10:2184.
doi: 110.3389/fimmu.2019.02184

Leptospirosis Pathophysiology: Into the Storm of Cytokines.
Cagliero J, Villanueva SYAM, Matsui M.
Front Cell Infect Microbiol. 2018 Jun 20;8:204.
doi: 10.3389/fcimb.2018.00204. eCollection 2018. Review.

High level of IL-10 expression in the blood of animal models possibly relates to resistance against leptospirosis
M. Matsui, L. Roche, M.-E. Soupé-Gilbert, M. Hasan, D. Monchy, C. Goarant.
Cytokine 2017; 11;96:144-151

Cytokine and chemokine expression in kidneys during chronic leptospirosis in reservoir and susceptible animal models.
M. Matsui, L. Roche, S. Geroult, M.-E. Soupé-Gilbert, D. Monchy, M. Huerre, C. Goarant.
PLoS One 2016; 11(5):e0156084

Papers – Dengue & Arbovirosis


An overview of mosquito vectors of Zika virus.
Boyer S, Calvez E, Chouin-Carneiro T, Diallo D, Failloux AB.
Microbes Infect. 2018 Mar 2. pii: S1286-4579(18)30039-X. doi: 10.1016/j.micinf.2018.01.006. 


Dengue-1 virus and vector competence of Aedes aegypti (Diptera: Culicidae) populations from New Caledonia.
Calvez E, Guillaumot L, Girault D, Richard V, O’Connor O, Paoaafaite T, Teurlai M, Pocquet N, Cao-Lormeau VM, Dupont-Rouzeyrol M.
Parasit Vectors. 2017 Aug 9;10(1):381. doi: 10.1186/s13071-017-2319-x.

A neutralization assay for Zika and Dengue viruses using a real-time PCR-based endpoint assessment
Wilson HL, Tran T, Druce J, Dupont-Rouzeyrol M, Catton M.
J Clin Microbiol. 2017 pii: JCM.00673-17. doi: 10.1128/JCM.00673-17.

Socioeconomic and environmental determinants of dengue transmission in an urban setting: an ecological study in Nouméa, New Caledonia.
Zellweger M, Cano J,  Mangeas M, Taglioni F, Mercier A, Despinoy M, Menkès C, Dupont-Rouzeyrol M, Nikolay B and Teurlai M. 
PLoS Negl Trop Dis. 2017 11(4):e0005471.

Zika virus infection and myasthenia gravis: Report of 2 cases.
Molko N, Simon O, Guyon D, Biron A, Dupont-Rouzeyrol M, Gourinat AC.
Neurology. 2017 Feb 10. pii: 10.1212


Vertical Transmission of Dengue Virus in the Peripartum Period and Viral Kinetics in Newborns and Breast Milk: New Data.
Arragain L*, Dupont-Rouzeyrol M*, O’Connor O, Sigur N, Grangeon JP, Huguon E, Dechanet C, Cazorla C, Gourinat AC, Descloux E.
J Pediatric Infect Dis Soc. 2016. pii: piw058.

Global spread of chikungunya virus a lesson for Aedes-transmitted arboviruses.
Duarte dos Santos C, Dupont-Rouzeyrol M, Sam IC, Roques P. CAB
Reviews. 2016 11(18):1-12.

 Zika virus infection as an unexpected finding in a Leptospirosis patient.
Biron A, Cazorla C, Amar J, Pfannstiel A, Dupont-Rouzeyrol M, Goarant C.
JMM Case Rep. 2016 3. doi: 10.1099

Infectious Zika viral particles in breastmilk
Dupont-Rouzeyrol M, Biron A, O’Connor O, Huguon E, Descloux E. .
Lancet. 2016 Mar 12;387(10023):1056.

Differential Susceptibilities of Aedes aegypti and Aedes albopictus from the Americas to Zika Virus
Chouin-Carneiro T, Vega-Rua A, Vazeille M, Yebakima A, Girod R, Goindin D, Dupont-Rouzeyrol M, Lourenço-de-Oliveira R, Failloux AB.
PLoS Negl Trop Dis. 2016 Mar 3;10(3):e0004543.

Whole-Genome Sequencing Analysis from the Chikungunya Virus Caribbean Outbreak Reveals Novel Evolutionary Genomic Elements.
Stapleford KA, Moratorio G, Henningsson R, Chen R, Matheus S, Enfissi A, Weissglas-Volkov D, Isakov O, Blanc H, Mounce BC, Dupont-Rouzeyrol M, Shomron N, Weaver S, Fontes M, Rousset D, Vignuzzi M.  PLoS Negl Trop Dis. 2016 Jan 25;10(1):e0004402.

Genetic Diversity and Phylogeny of Aedes aegypti, the Main Arbovirus Vector in the Pacific.
Calvez E, Guillaumot L, Millet L, Marie J, Bossin H, Rama V, Faamoe A, Kilama S, Teurlai M, Mathieu-Daudé F, Dupont-Rouzeyrol M. 
PLoS Negl Trop Dis. 2016 Jan 22;10(1):e0004374.


Co-infection with Zika and Dengue Viruses in 2 Patients, New Caledonia, 2014.
Dupont-Rouzeyrol M, O’Connor O, Calvez E, Daurès M, John M, Grangeon JP, Gourinat AC.
Emerg Infect Dis. 2015. 21(2):381-2.

Detection of zika virus in urine.
Gourinat AC*, O’Connor O*, Calvez E, Goarant C, Dupont-Rouzeyrol M. 
Emerg Infect Dis. 2015. 21(1):84-6.


Epidemiological and molecular features of dengue virus type-1 in New Caledonia, South Pacific, 2001-2013.
Dupont-Rouzeyrol M, Aubry M, O’Connor O, Roche C, Gourinat AC, Guigon A, Pyke A, Grangeon JP, Nilles E, Chanteau S, Aaskov J, Cao-Lormeau VM. 
Virol J. 2014. 31;11:61.

The emm-cluster typing system for group A Streptococcus identifies epidemiologic similarities across the Pacific region
Baroux N, D’Ortenzio E, Amédéo N, BakerC, Alsuwayyid BA, Dupont-Rouzeyrol M, O’Connor O, Steer A, Smeesters P.
Clin Infect Dis. 2014. 59(7):e84-92.

Isolation and partial characterization of bacteria (Pseudoalteromonas sp.) with potential antibacterial activity from a marine costal environment from New Caledonia.
Dufourcq R, Chalkiadakis E, Fauchon M, Deslandes E, Kerjean V, Chanteau S, Petit E, Guezennec J, Dupont-Rouzeyrol M. 
Lett Appl Microbiol. 2014. 58(2):102-8.


Breast milk as a possible route of vertical transmission of dengue virus?
Barthel A, Gourinat AC, Cazorla C, Joubert C, Dupont-Rouzeyrol M, Descloux E. 
Clin Infect Dis. 2013 Aug;57(3):415-7.

Partial characterization of an exopolysaccharide secreted by a marine bacterium, Vibrio neocaledonicus sp. nov., from New Caledonia.
Chalkiadakis E, Dufourcq R, Schmitt S, Brandily C, Kervarec N, Coatanea D, Amir H, Loubersac L, Chanteau S, Guezennec J, Dupont-Rouzeyrol M, Simon-Colin C.
J Appl Microbiol. 2013 Jun;114(6):1702-12.


Chikungunya virus and the mosquito vector Aedes aegypti in New Caledonia (South Pacific Region).
Dupont-Rouzeyrol M, Caro V, Guillaumot L, Vazeille M, D’Ortenzio E, Thiberge JM, Baroux N, Gourinat AC, Grandadam M, Failloux AB.
Vector Borne Zoonotic Dis. 2012. 12(12):1036-41.

Use of serum and blood samples on filter paper to improve the surveillance of dengue in Pacific Island Countries.
Aubry M, Roche C, Dupont-Rouzeyrol M, Aaskov J, Viallon J, Marfel M, Lalita P, Elbourne-Duituturaga S, Chanteau S, Musso D, Pavlin BI, Harrison D, Kool JL, Cao-Lormeau VM.
J Clin Virol. 2012 Sep;55(1):23-9.

Lower respiratory infections among hospitalized children in New Caledonia: a pilot study for the Pneumonia Etiology Research for Child Health project.
Mermond S, Zurawski V, D’Ortenzio E, Driscoll AJ, DeLuca AN, Deloria-Knoll M, Moïsi JC, Murdoch DR, Missotte I, Besson-Leaud L, Chevalier C, Debarnot V, Feray F, Noireterre S, Duparc B, Fresnais F, O’Connor O, Dupont-Rouzeyrol M, Levine OS. 
Clin Infect Dis. 2012 Apr;54 Suppl 2:S180-9.


Aetiology of community-acquired pneumonia in hospitalized adult patients in New Caledonia.
Mermond S, Berlioz-Arthaud A, Estivals M, Baumann F, Levenes H, Martin PM.
Trop Med Int Health. 2010 Dec;15(12):1517-24.


Real-time PCR detection of gyrA and parC mutations in Streptococcus pneumoniae.
Page S, Vernel-Pauillac F, O’Connor O, Bremont S, Charavay F, Courvalin P, Goarant C, Le Hello S.  Antimicrob Agents Chemother. 2008 Nov;52(11):4155-8.

Regional Course about Leptospirosis

2017_lorcRegional course  about Leptospirosis

held from 13 to 17 November 2017

Opening session by Mrs. Valentine Eurisouké, member of government in charge of health.






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